Nonenzymatic transformations of enzymatically generated N -acetyldopamine quinone and isomeric dihydrocaffeiyl methyl amide quinone
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چکیده
منابع مشابه
Characterization of products from the reactions of N-acetyldopamine quinone with N-acetylhistidine.
When insects harden or sclerotize their exoskeletons, quinones of N-acetylated catecholamines such as N-acetyldopamine (NADA) undergo nucleophilic addition reactions with amino acids such as histidine in cuticular proteins. To determine the products that might form when this type of reaction occurs during cuticle sclerotization, the reactions between electrochemically prepared NADA quinone and ...
متن کاملDisulfide bonds are generated by quinone reduction.
The chemistry of disulfide exchange in biological systems is well studied. However, very little information is available concerning the actual origin of disulfide bonds. Here we show that DsbB, a protein required for disulfide bond formation in vivo, uses the oxidizing power of quinones to generate disulfides de novo. This is a novel catalytic activity, which to our knowledge has not yet been d...
متن کاملActivity of quinone alkylating agents in quinone-resistant cells.
The role of the quinone group in the antitumor activity of quinone alkylating agents, such as mitomycin C and 2,5-diaziridinyl-3,5-bis(carboethoxyamino)-1,4-benzoquinone, is still uncertain. The quinone group may contribute to antitumor activity by inducing DNA strand breaks through the formation of free radicals and/or by influencing the alkylating activity of the quinone alkylators. The cytot...
متن کاملActivity of Quinone Alkylating Agents in Quinone-resistant Cells1
The role of the quinone group in the antitumor activity of quinone alkylating agents, such as mitomycin C and 2,5-diaziridinyl-3,5bis(carboethoxyamino)-l,4-benzoquinone, is still uncertain. The quinone group may contribute to antitumor activity by inducing DNA strand breaks through the formation of free radicals and/or by influencing the alkylating activity of the quinone alkylators. The cytoto...
متن کاملElectrocoagulation of quinone pigments.
Some representative quinones, viz. one naphthoquinone (plumbagin) and five anthraquinones (alizarin, purpurin, chrysazin, emodin, and anthrarufin), were subjected to electrocoagulation. It was found that the rate and extent of coagulation of these compounds appears to correlate with the number and relative position of their phenolic substituent groups, and that all of the coagulated quinones co...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1989
ISSN: 0014-5793
DOI: 10.1016/0014-5793(89)81118-4